Aminogam® products contain sodium hyaluronate and four synthetic amino acids (glycine, L-leucine, L-proline and L-lysine Hcl).1,2,3
Sodium hyaluronate is the sodium salt of hyaluronic acid. Hyaluronic acid is a key component of connective tissue and promotes tissue repair. Its use has also been reported in dentistry to exert an anti-inflammatory effect and to control gingival bleeding.5
Hyaluronic acid has been shown to promote cell proliferation, differentiation and motility.6
The amino acids present in Aminogam® are intended to promote the formation of collagen.2,3 The availability of amino acids, such as those present in Aminogam®, is necessary in wound repair due to increased metabolic activity.6,7
The four amino acids present in Aminogam® favour wound healing by collagenogenesis and extracellular matrix (ECM) formation.7
Injury of the oral mucosa
The oral mucosa is made up of a rapidly proliferating and continually renewing sheet of epithelial cells which serve a number of specialised functions, including acting as a barrier between the host and the potentially hostile oral environment.8
Injury of the oral mucosa is a relatively common finding in dental practice which can result from physical, chemical or thermal trauma. Such injuries can originate from accidental dental biting, sharp or pointing food stuff, sharp edges of teeth or overzealous tooth brushing. Additionally, injury to the oral mucosa can result from iatrogenic damage during treatment (for example, oral surgery), or other procedures involving the oral cavity, for example intubation during general anaesthesia.9
Aminogam® products are CE marked medical devices that can be used as an adjuvant in the oral-gingival tissue regeneration process. 1,2,3
Aminogam® products are available in three presentations; a gel, a spray and a mouthwash.
Aminogam® Gel facilitates rapid regeneration of oral tissue and maintenance of the ideal moisture conditions to promote re-epithelisation of the affected area.
Aminogam® Gel provides a protective action, promoting fast healing of ulcerative and erosive lesions, and oral wounds.1
Aminogam® Spray aids the process of tissue regeneration, favouring rapid recovery to areas of injury along with simultaneous reduction in pain.
Aminogam® Spray exerts a protective nature, stimulating fibroblast growth and facilitating the physiological re-epithelialisation of the injured area. The spray formulation allows for easy application, even in the most difficult to reach areas of the mouth.2
Aminogam® Mouthwash facilitates the oral tissue regeneration process, promoting the physiological re-epithelialisation of injured areas. It exerts a protective nature, favouring the fast recovery of areas of injury and simultaneous reduction in pain.3